Dosing
Estrogen
There are four primary methods of administering estrogen:
| Type | Recommended Dose | Notes |
|---|---|---|
| Pills | 2-6mg daily | Sublingual Dosing WILL result in high spikes of Estrogen, improving efficiency but may cause unwanted effects e.g mood swings. Swallowing leads to more consistent levels. |
| Gel | -- | Applied to CLEAN and DRY skin, typically below the waist. |
| Patches | 50-200mcg twice weekly | Typical administration is below the Waist. |
| Injections | -- | Cheapest overall and best for monotherapy. See "Injections" chart for specifics with dosing. |
Estrogen Injections
| Type | Recommended Dose | Notes |
|---|---|---|
| Valerate | 3-4mg ~Every 5 days | -- |
| Cypionate | 4-8mg ~Every 7 Days | -- |
| Enanthate | 4-8mg ~Every 7 Days | -- |
| Undecylate (MCT Oil) | 15-25mg ~21 Days | -- |
| Undecylate (Caster Oil) | 40-60mg ~31 Days | -- |
Testosterone Blockers
These medications reduce testosterone levels. Below are some common options:
| Drug Name | Recommended Dose | Notes |
|---|---|---|
| Cyproterone Acetate | 12.5mg every other day | Cases of Hyperprolactinemia have been found. Currently the CHEAPEST option and reguarded to be one of the safest. |
| Bicalutamide | 50mg daily | Non-steroidal; blocks androgen receptors. |
| Spironolactone | 100-200mg daily | Also a diuretic; may increase urination and potassium levels. |
| GnRH Agonists (e.g., Leuprorelin) | -- | The most expensive option, see "GnRH T-Blocker Options" for details |
GnRH T-Blocker Options
| Drug Name | Recommended Dose | Method of administering | Notes |
|---|---|---|---|
| Leuprolide Acetate | -- | Injection | -- |
| Triptorelin | -- | Injection | Branded as "Decapeptyl" in the UK |
| Buserelin | -- | Injection OR Nasel Spray | -- |
Progesterone
| Type | Recommended Dose | Notes |
|---|---|---|
| Medroxyprogesterone Acetate | -- | |
| Progesterone Gel | -- | |
| -- |
Other
Miscelanious drugs related to Mtf HRT
| Type | Recommended Dose | Notes |
|---|---|---|
| Raloxifene | ~60mg Daily | Can prevent breast development while on Estrogen. |
| Finasteride | 5mg Daily | 5-alpha reductase inhibitor, NOT a T-Blocker. |
| Dutasteride | 0.5mg Daily | 5-alpha reductase inhibitor, NOT a T-Blocker. |