Dosing
Estrogen
There are four primary methods of administering estrogen:
| Type |
Recommended Dose |
Notes |
| Pills |
2-6mg daily |
Sublingual Dosing WILL result in high spikes of Estrogen, improving efficiency but may cause unwanted effects e.g mood swings. Swallowing leads to more consistent levels. |
| Gel |
-- |
Applied to CLEAN and DRY skin, typically below the waist. |
| Patches |
50-200mcg twice weekly |
Typical administration is below the Waist. |
| Injections |
-- |
Cheapest overall and best for monotherapy. See "Injections" chart for specifics with dosing. |
Estrogen Injections
| Type |
Recommended Dose |
Notes |
| Valerate |
3-4mg ~Every 5 days |
-- |
| Cypionate |
4-8mg ~Every 7 Days |
-- |
| Enanthate |
4-8mg ~Every 7 Days |
-- |
| Undecylate (MCT Oil) |
15-25mg ~21 Days |
-- |
| Undecylate (Caster Oil) |
40-60mg ~31 Days |
-- |
Injection & Supplies Guide
Testosterone Blockers
These medications reduce testosterone levels. Below are some common options:
| Drug Name |
Recommended Dose |
Notes |
| Cyproterone Acetate |
12.5mg every other day |
Cases of Hyperprolactinemia have been found. Currently the CHEAPEST option and reguarded to be one of the safest. |
| Bicalutamide |
50mg daily |
Non-steroidal; blocks androgen receptors. |
| Spironolactone |
100-200mg daily |
Also a diuretic; may increase urination and potassium levels. |
| GnRH Agonists (e.g., Leuprorelin) |
-- |
The most expensive option, see "GnRH T-Blocker Options" for details |
GnRH T-Blocker Options
| Drug Name |
Recommended Dose |
Method of administering |
Notes |
| Leuprolide Acetate |
-- |
Injection |
-- |
| Triptorelin |
-- |
Injection |
Branded as "Decapeptyl" in the UK |
| Buserelin |
-- |
Injection OR Nasel Spray |
-- |
Other
Miscelanious drugs related to Mtf HRT
| Type |
Recommended Dose |
Notes |
| Raloxifene |
~60mg Daily |
Can prevent breast development while on Estrogen. |
| Finasteride |
5mg Daily |
5-alpha reductase inhibitor, NOT a T-Blocker. |
| Dutasteride |
0.5mg Daily |
5-alpha reductase inhibitor, NOT a T-Blocker. |